Case Study : AI-Driven Agrochemical Discovery

case study
Published on 17 September 2025

Challenge:

  • Global agriculture faces major crop losses due to pests & insects.
  • Traditional pesticide discovery is slow, costly, and heavily experimental.
  • Growing concerns: resistance, safety, and environmental sustainability.

Our Goal:

Design next-generation pesticide & insecticide inhibitors using AI + physics-based models, reducing time and cost before experimental validation.

AI + Physics-Based Approach:

  • AI Models
  • Deep learning trained on agrochemical datasets.

  • Generative algorithms to design novel scaffolds.
  • Physics-Based Models
  • Docking & molecular dynamics for binding affinity.

  • Quantum chemistry for stability & energy scoring.

Key Outcomes:

  • Explored millions of virtual molecules → narrowed to top candidates.
  • Designed novel chemotypes beyond existing pesticides.
  • Predicted high potency & selectivity vs. pest targets.
  • In silico tox: favorable safety profiles.

Status:

  1. Computational pipeline complete.
  2. Experimental validation pending (synthesis & biological testing next).
  3. Potential for safer, sustainable crop protection solutions.

Conclusion:

This project demonstrates how AI + physics-based models can:

  • Accelerate agrochemical discovery.
  • Deliver innovative, environmentally responsible inhibitors.
  • Cut reliance on costly broad-screening campaigns.